PDRN (Polydeoxyribonucleotides) Healer / PDRN S

If you want to improve your complexion (think Korean glass skin), smoothen out acne scars or shave off years with younger looking eyes, our range of PDRN (Polydeoxyribonucleotides)minimally invasive injectable solutions may just be your answer.  

Salmon is widely consider as one of the most nutritious foods on the planet, and is credited with everything from extending a person’s lifespan to preventing heart attacks and cancer. Not only does salmon possess one of the highest omega-3 contents, it is also packed with tons of other vitamins and minerals as well. For beauty and health lovers, the potential of this fish takes shape as mains, pills, drinks and topical creams. Scientific studies done have proven beyond doubt that just a small percentage of salmon DNA cream rubbed onto the skin will improve upon its elasticity over time, and one couldn’t help but wonder what can be achieved to have the essence injected directly into the skin!

PDRN (Polydeoxyribonucleotides) HEALER [AS FACIAL ENHANCERS]

PDRN Healer hailed from South Korea is a novel concept treatment for aging, tired skin and is currently one of the most sought after anti-aging treatment. An injectable polynucleotide (PN) skin booster consisting of fragments of DNA derived from germ cells of salmon, the added salmon PN/PDRN supplements the action of our innate source of PN/PDRN, increasing the metabolic activity of cells in the skin called fibroblasts to start producing collagen again. PDRN (Polydeoxyribonucleotides) teaches aging skin cells to behave in a youthful manner, helping to improve skin elasticity, tone and texture by promoting the regeneration of collagen and skin thickness. Touted as possibly the most advanced anti-wrinkle, anti-sag and skin brightening treatment, PDRN (Polydeoxyribonucleotides) Healer repairs skin cells and facilitates collagen growth in a nutshell. Rejuvenating lackluster complexions to get the desirable glow and radiance of youthful looking skin, PDRN (Polydeoxyribonucleotides)Healer is also affectionately called 婴儿针。

PDRN (Polydeoxyribonucleotides) is KFDA approved for injection in the skin.


  • Improves uneven skin discoloration and pigmentation
  • Improves skin tone and elasticity
  • Improves skin texture
  • Improves fine lines and softens the appearance of deep wrinkles
  • Restores protective layers of skin
  • Balances sebum and moisture of skin for better hydration and oil control
  • Reduces pore size
  • Reduces dead skin cells and increases cellular turnover and renewal

Apart from overall parts of the face, PDRN (Polydeoxyribonucleotides) Healer works equally well on oft-neglected body parts such as the neck and back of hands, erasing telltale signs of aging to keep others second guessing your actual age. 

PDRN (Polydeoxyribonucleotides) In Comparison With Other Injectable Treatments

PDRN (Polydeoxyribonucleotides)


PCL Biostimulating Filler





Poly-L-Lactic Acid

Polycaprolactone (PCL)

100% Pure High Concentration & Low Molecular Weight Hyaluronic Acid

Hyaluronic Acid


Multiple Microinjection

Fanning Tech

Injections or Fanning Technique

Specialised BAP Technique-5 injection per side

Multiple micro injection









Multiple insect bite-like swelling

Mild to moderate facial swelling

Mild swelling and injection marks

Minimal to no downtime

Multiple injection marks


Collagen Stimulation

Pore Reduction

Acne Scarring






Fine Lines / Wrinkles

Skin-Tightening / Lifting





Treatment Regime

3 sessions of monthly intervals

2 sessions of monthly intervals

1 session every 12-24 months

2 sessions of monthly intervals

3 sessions of monthly intervals

What kind of results will I see?

3 – 5 days after first administration*

Skin texture softened
Sebum secretion reduced due to balance between oil and moisture of skin

2-4 weeks after second administration*

Skin elasticity improved by regeneration of collagen
Fine wrinkles around eyes and overall face improved
Pore size and dead cells reduced

4-6 weeks after third administration*

Natural lifting effect by improvement of skin elasticity
Skin volume filled out from dermis layer of skin

6-8 weeks after fourth administration*

Rejuvenates skin – gives you healthy youthful radiant skin
*individual results may vary

PDRN (Polydeoxyribonucleotides) S [FOR SCARS]

Our skin is a seamless organ much like a piece of silk protecting the valuable assets wrapped within. Just like how a small tear or run in the fabric can make a big difference to how it looks, the same goes for our skin with scars. Some scars give us character and perfect ice-breaking stories we’ll never forget, but the majority are nothing more than pesky imperfections we'd rather do without.

A study published in March 2010 to investigate the effect of rubbing salmon DNA on human skin showed a significant improvement in skin elasticity, texture and hydration just by this simple action alone, and PDRN has demonstrated promising results in the clinical treatment of diabetic foot ulcers and burns. As PDRN evolved, new uses were found for this exceptional skin healing agent, with conditions that required an activation of wound-healing processes such as depressed scars getting good reviews from its use.  

The composition of PDRN (Polydeoxyribonucleotides) S makes it more viscous and gel-like compared to PDRN (Polydeoxyribonucleotides) Healer, and it acts partially like a dermal filler to fill up sunken scars. At the same time, PDRN (Polydeoxyribonucleotides) S boasts the same rejuvenating capabilities as PDRN (Polydeoxyribonucleotides) Healer, inducing collagen reproduction at the dermis to heal and improve the appearance scars. PDRN (Polydeoxyribonucleotides) S microinjections leads to improvement of most types of acne scarring such as box scars, rolling scars, and icepick scars. An exceedingly rich source of polynucleotides which are the basic building blocks of our very own DNA, PDRN (Polydeoxyribonucleotides) “activates” the healing properties of skin by providing these building blocks for DNA synthesis. Either as a standalone treatment or best combined with subcision and/or resurfacing lasers for optimal outcome, PDRN (Polydeoxyribonucleotides) S gives gratifying results with very manageable downtime.

PDRN (Polydeoxyribonucleotides) I [FOR AGEING EYES]

While PDRN (Polydeoxyribonucleotides) S is more viscous, PDRN (Polydeoxyribonucleotides) I is less viscous in texture compared to PDRN (Polydeoxyribonucleotides) Healer, specifically formulated for the delicate skin around the eyes without causing lumpiness and prolonged downtime. PDRN (Polydeoxyribonucleotides) I greatly improves the elasticity of undereye skin, effectively reduces fine lines, Crow’s feet and dark eye circles after a recommended primary course of 3 treatment sessions done at monthly intervals. 


Am I a suitable candidate for PDRN (Polydeoxyribonucleotides) microinjections?
After around 20 years of age, the ability of synthesizing DNA in our body starts to fall. As aging progresses, even antioxidants and sunscreen will be insufficient to fully heal the skin due to insufficient stores of naturally-occurring DNA stores.  Acne marks stay for longer than welcomed, pigmentation not seen in your 20s surfaces, fine lines start to creep all over the place and wrinkles deepened to become permanently etched into the skin. Hence, it is vital to maintain the integrity of our skin’s DNA for overall skin health to delay or reverse the onslaught of these undesirable signs of skin aging.

What is the procedure like?
Numbing cream is applied prior to treatment for 10 to 15 minutes to minimize any pain or discomfort. Multiple microinjections are then administered by our trained doctors under a constant stream of cold air emitted from the Zimmer air cooler to make the whole procedure even more tolerable. 

What kind of downtime do I expect?
Post treatment, you will be left with multiple “insect-bite-like” swellings, ranging from 3 to 8mm in size over the treated area(s). These bumps are normal and generally disappears within 1 to 3 days. You may wish to undergo an add-on LED Healite treatment which significantly shortens the recovery time. Use of our Calecim professional serum containing 80% stem cell proteins will quicken recovery. Learn more about Calecim at www.freia247.sg.

How often do I need to get the treatment done?
A primary course of 3 treatments, done 3-4 weeks apart is recommended for optimal results. After the intensive course of treatment, you can repeat the treatment every 4-6 months to maintain or further enhance your skin quality. 

Can PDRN (Polydeoxyribonucleotides) be combined with other procedures?
PDRN (Polydeoxyribonucleotides) can be performed as a standalone procedure or combined with lasers and other injectables for an even better outcome. For the coveted “glass skin” complexion that is well hydrated, translucent and luminous with just the right amount of seen, enquire about our Baby Skin treatment combining the synergistic effects of PDRN (Polydeoxyribonucleotides) and hyaluronic acid Skinboosters with a carefully curated selection of complexion enhancers. 

Uneven skin gives even make-up a hard time.

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